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Showing posts from November, 2021

Can 7,8-Dihydroxyflavone Be Used To Treat Neurodegenerative Diseases?

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  7,8-DIHYDROXYFLAVONE History 7,8-Dihydroxyflavone (7,8-DHF)  is a synthetic flavonoid that was originally discovered in a study to screen small molecules that can activate what is called tropomyosin-related kinase B ( The specific receptor of TrkB) is called brain-derived neurotrophic factor (BDNF) in the human body that acts on this receptor, and it cannot be used due to malabsorption of the brain. 7,8-DHF was found to be an effective mimic of BDNF and can act on TrkB in a similar way. This means that 7,8-DHF can theoretically produce similar effects to BDNF in the brain, and is theoretically more useful for treatment due to its better absorption and ability to cross the blood-brain barrier.   What is 7,8-DIHYDROXYFLAVONE(38183-03-8) Powder? 7,8-dihydroxyflavone, also known as the 7,8-DHF or Tropoflavin, which is a naturally occurring flavonoid produced by several plants, including the weed Tridax procumbens (coalbuttons or tridax daisy) and the tree Godmania aesculifo...

Nootropics Magnesium L Threonate: What Are Its Benefits For The Brain?

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Why we need Magnesium? Before we can delve into the Magnesium L-Threonate  nootropic supplement , you may need to understand about its key predecessor. Magnesium is a significant micronutrient, which is actively involved in several bodily processes. The element has a hold over muscle contraction and relaxation, protein synthesis, and neuronal functions. Besides, it regulates blood sugar and maintains blood pressure. Although you can take Magnesium per se, most of these supplements are chelated or bonded with amino acids. Chelation improves absorption, stability, and bioavailability of minerals. The concentration of Magnesium is higher in the brain than in any other body part. It reverses brain aging by enhancing plasticity and synaptic density, which are significant factors for cognitive processing. Magnesium deficiency accounts for  bipolar disorders , dementia, Alzheimer’s disease, acute brain injury, schizophrenia, seizures, depression, among other conditions. The therapeut...