Can 7,8-Dihydroxyflavone Be Used To Treat Neurodegenerative Diseases?
7,8-DIHYDROXYFLAVONE History 7,8-Dihydroxyflavone (7,8-DHF) is a synthetic flavonoid that was originally discovered in a study to screen small molecules that can activate what is called tropomyosin-related kinase B ( The specific receptor of TrkB) is called brain-derived neurotrophic factor (BDNF) in the human body that acts on this receptor, and it cannot be used due to malabsorption of the brain. 7,8-DHF was found to be an effective mimic of BDNF and can act on TrkB in a similar way. This means that 7,8-DHF can theoretically produce similar effects to BDNF in the brain, and is theoretically more useful for treatment due to its better absorption and ability to cross the blood-brain barrier. What is 7,8-DIHYDROXYFLAVONE(38183-03-8) Powder? 7,8-dihydroxyflavone, also known as the 7,8-DHF or Tropoflavin, which is a naturally occurring flavonoid produced by several plants, including the weed Tridax procumbens (coalbuttons or tridax daisy) and the tree Godmania aesculifo...